Fetal evaluation by real-time imaging

The application of real-time imaging to the study of fetal morphology and function is an exciting advance. Rapid accurate study of fetal dynamics is possible with this apparently safe, noninvasive technique. Animal studies have revealed the general physiology of fetal breathing movements, which are now under extensive investigation with real-time imaging in the human. There is evidence for circadian rhythm of human fetal breathing movements as well as a relationship to maternal substrate loading. The presence of fetal breathing movements of the rapid irregular type may be a reassuring sign in the presence of other indicators of fetal compromise. Using real-time B-scan imaging, we have found long periods of apnea in pregnancies with normal perinatal outcome. As suggested in the animal studies, changes in fetal breathing patterns prior to fetal death may be more complex than originally thought. The techique of real-time B-scan imaging with precise definition of apnea, general movements, and fetal breathing will provide valuable information on which to base our evaluation of the clinical usefulness of fetal breathing movement studies in the management of pregnancy.