Standardized Clinical Assessment and Management Plan Enhances Neonatal Outcomes in Prenatally Diagnosed Congenital

Lior Kashani Ligumsky1,2, Angela Desmond3, Vanessa Kirschner1

  • 1Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.

Pediatric Cardiology
|June 14, 2025
PubMed

Insights

Implementing a Standardized Clinical Assessment and Management Plan (SCAMP) for congenital heart disease (CHD) improved survival rates and reduced hospital stays for newborns. This standardized approach optimizes care for pregnancies complicated by fetal CHD.

Area of Science:

  • Perinatal Medicine
  • Neonatal Cardiology
  • Public Health Interventions

Background:

  • Congenital heart disease (CHD) is a major cause of newborn illness and death.
  • Optimizing birth timing and mode is crucial for managing pregnancies with fetal CHD.
  • Standardized protocols can improve outcomes in complex neonatal conditions.

Purpose of the Study:

  • To evaluate the impact of a Standardized Clinical Assessment and Management Plan (SCAMP) on neonatal outcomes in pregnancies with fetal CHD.
  • To assess changes in survival to hospital discharge, birth weight, and hospital length of stay after SCAMP implementation.
  • To compare outcomes between neonates with prenatally diagnosed CHD before and after SCAMP adoption.

Main Methods:

  • Retrospective cohort study comparing historical and intervention groups of neonates with prenatally diagnosed CHD.
  • Data collected from five University of California medical centers.
  • Statistical analyses included t-tests for continuous variables and chi-square tests for categorical variables.

Main Results:

  • Overall neonatal survival to discharge significantly increased post-SCAMP (91.1% vs. 83.1%, p=0.04).
  • Survival following cesarean birth improved (89.1% vs. 78.1%, p=0.04), with no significant difference for other birth modes.
  • Mean birth weight increased (2977g vs. 2838g, p=0.01), and hospital length of stay significantly decreased (11.5 vs. 26 days, p<0.01).

Conclusions:

  • SCAMP implementation is associated with improved neonatal survival rates for CHD-affected pregnancies.
  • Standardized perinatal management through SCAMP leads to better birth weights and shorter hospitalizations.
  • These findings highlight the value of standardized care pathways in optimizing outcomes for neonates with congenital heart disease.

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