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Standardized Clinical Assessment and Management Plan Enhances Neonatal Outcomes in Prenatally Diagnosed Congenital
Lior Kashani Ligumsky1,2, Angela Desmond3, Vanessa Kirschner1
1Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Insights
Implementing a Standardized Clinical Assessment and Management Plan (SCAMP) for congenital heart disease (CHD) improved survival rates and reduced hospital stays for newborns. This standardized approach optimizes care for pregnancies complicated by fetal CHD.
Area of Science:
- Perinatal Medicine
- Neonatal Cardiology
- Public Health Interventions
Background:
- Congenital heart disease (CHD) is a major cause of newborn illness and death.
- Optimizing birth timing and mode is crucial for managing pregnancies with fetal CHD.
- Standardized protocols can improve outcomes in complex neonatal conditions.
Purpose of the Study:
- To evaluate the impact of a Standardized Clinical Assessment and Management Plan (SCAMP) on neonatal outcomes in pregnancies with fetal CHD.
- To assess changes in survival to hospital discharge, birth weight, and hospital length of stay after SCAMP implementation.
- To compare outcomes between neonates with prenatally diagnosed CHD before and after SCAMP adoption.
Main Methods:
- Retrospective cohort study comparing historical and intervention groups of neonates with prenatally diagnosed CHD.
- Data collected from five University of California medical centers.
- Statistical analyses included t-tests for continuous variables and chi-square tests for categorical variables.
Main Results:
- Overall neonatal survival to discharge significantly increased post-SCAMP (91.1% vs. 83.1%, p=0.04).
- Survival following cesarean birth improved (89.1% vs. 78.1%, p=0.04), with no significant difference for other birth modes.
- Mean birth weight increased (2977g vs. 2838g, p=0.01), and hospital length of stay significantly decreased (11.5 vs. 26 days, p<0.01).
Conclusions:
- SCAMP implementation is associated with improved neonatal survival rates for CHD-affected pregnancies.
- Standardized perinatal management through SCAMP leads to better birth weights and shorter hospitalizations.
- These findings highlight the value of standardized care pathways in optimizing outcomes for neonates with congenital heart disease.
Abstract:
Congenital heart disease (CHD) remains a leading cause of neonatal morbidity and mortality. The University of California Fetal Consortium implemented a Standardized Clinical Assessment and Management Plan (SCAMP) to optimize birth timing and mode of birth in pregnancies complicated by fetal CHD. This study evaluates the impact of SCAMP implementation on neonatal outcomes, specifically survival to hospital discharge, birth weight, and hospital length of stay. A retrospective cohort study was conducted comparing neonates with prenatally diagnosed CHD before (historical cohort) and after (intervention cohort) SCAMP implementation. Neonatal data, including mode of birth, birth weight, survival to discharge, and CHD classification was collected from five UC medical centers. Comparative analyses were performed using t-tests for continuous variables and chi-square tests for categorical variables. A total of 414 neonates met inclusion criteria (167 in the historical cohort, 247 in the intervention cohort). The overall neonatal survival rate to discharge was significantly higher in the intervention cohort (91.1% vs. 83.1%, p = 0.04). Survival following cesarean birth was also improved in the intervention cohort (89.1% vs. 78.1%, p = 0.04), while no significant differences were found for induction of labor or spontaneous vaginal births. Birth weight was significantly higher post-SCAMP (2977 g vs. 2838 g, p = 0.01), and hospital length of stay was significantly shorter (11.5 vs. 26 days, p < 0.01). Survival differences by CHD risk classification were not statistically significant. SCAMP implementation was associated with improved neonatal survival, increased birth weight, and reduced hospitalization duration in CHD-affected pregnancies. These findings underscore the importance of standardized perinatal management in optimizing outcomes for neonates with CHD.
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