Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Changing aspects of radiation enteropathy.

L Morgenstern, M Hart, D Lugo

    Archives of Surgery (Chicago, Ill. : 1960)
    |November 1, 1985
    PubMed
    Summary

    Radiation enteropathy patients show fewer mucosal issues but more serosal reactions. Surgical management evolved with new radiation techniques and nutritional support, impacting outcomes for abdominal and pelvic cancer radiation therapy.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Novel sediment inocula enhance co-digestion of sewage sludge and landfill leachate: Links between microbial assembly and process stability.

    Bioresource technology·2026
    Same author

    High output power, single mode, and TEM<sub>00</sub> operation of a multiple gain chip VECSEL using a twisted-mode configuration.

    Optics express·2023
    Same author

    Rapid quasi-periodic oscillations in the relativistic jet of BL Lacertae.

    Nature·2022
    Same author

    Strong host-specific selection and over-dominance characterize arbuscular mycorrhizal fungal root colonizers of coastal sand dune plants of the Mediterranean region.

    FEMS microbiology ecology·2021
    Same author

    Laboratory biomarkers associated with COVID-19 severity and management.

    Clinical immunology (Orlando, Fla.)·2020
    Same author

    Plasma cell depletion with bortezomib in the treatment of refractory N-methyl-d-aspartate (NMDA) receptor antibody encephalitis. Rational developments in neuroimmunological treatment.

    European journal of neurology·2018

    Area of Science:

    • Gastroenterology
    • Radiation Oncology
    • Surgical Oncology

    Background:

    • Radiation enteropathy is a significant complication following abdominal or pelvic radiation therapy for malignant neoplasms.
    • Previous studies established intestinal obstruction as a primary complication requiring surgical intervention.

    Purpose of the Study:

    • To compare outcomes and management strategies for radiation enteropathy between two distinct patient cohorts treated at the same institution.
    • To identify changes in radiation enteropathy presentation and treatment over time.

    Main Methods:

    • Retrospective analysis of 52 patients treated between 1977-1984, compared to a historical cohort of 50 patients (1961-1977).
    • Review of surgical interventions, including intestinal resection and anastomotic bypass.
    • Evaluation of changes in radiation energy sources, surgical adjuncts, and nutritional support.

    Main Results:

    • Intestinal obstruction remained the principal complication in both series, with 96% requiring surgical intervention.
    • The later series exhibited less mucosal damage but increased serosal reaction ('serosal peel').
    • Increased utilization of elemental diets, parenteral nutrition, and long intestinal tubes in surgical management was observed.

    Conclusions:

    • Modern radiation therapy techniques (e.g., linear accelerators) may alter the manifestation of radiation enteropathy.
    • Advances in surgical management and nutritional support have influenced patient care.
    • Strategies to exclude small bowel from the pelvis and modifications in radiation fractionation are crucial considerations for managing radiation enteropathy.

    Related Experiment Videos