Theoretical formulation of sieving coefficient evaluation for membrane plasma separation

Three different sieving coefficient definitions were theoretically investigated. It has been shown that the local sieving coefficient, characterizing membrane property, can be calculated under specified assumptions from input-output measurements. In contrast, the evaluation of the device sieving coefficient, useful in kinetic modeling, is validated in a situation in which calculation of the local sieving coefficient is connected with substantial error. The relationship between different sieving coefficient definitions is also given.