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[Analysis of developmental function in 32 511 children with global developmental delay].

N N Xiong1, Z J Cui1, M Zhao1

  • 1Department of Health Care, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.

Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi
|June 15, 2025
PubMed
Summary
This summary is machine-generated.

Global developmental delay (GDD) affects more boys than girls, with fine motor skills being the most common area of concern. Most GDD cases involve mild delays, but severe language delays are more prevalent than in other domains.

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Area of Science:

  • Developmental Pediatrics
  • Neurodevelopmental Disorders
  • Child Psychology

Context:

  • Global developmental delay (GDD) is a significant concern in early childhood, impacting multiple developmental domains.
  • Understanding the clinical manifestations and demographic variations in GDD is crucial for targeted interventions.
  • This study analyzes neuro-psychobehavioral data from a large cohort of young children diagnosed with GDD.

Purpose:

  • To analyze the clinical symptoms and patterns of global developmental delay (GDD) in children aged 0.0 to 4.9 years.
  • To provide a scientific basis for the early intervention strategies for children diagnosed with GDD.
  • To identify specific domains of delay and demographic differences (gender, age) in GDD presentation.

Summary:

  • A large-scale study of 32,511 children with GDD revealed that boys are disproportionately affected (68.2%).
  • Fine motor delay was most frequent (85.1%), followed by social self-care (83.9%) and language (79.0%). Boys showed higher rates of delay in fine motor, adaptability, language, and social self-care domains.
  • While most delays were mild, severe language delay occurred more frequently than in other domains. Developmental delay in 4-5 domains was observed in 54.5% of cases, increasing with age.

Impact:

  • Findings highlight the need for gender-specific approaches in assessing and managing GDD.
  • The prevalence of fine motor and language delays underscores the importance of early screening and targeted therapies.
  • This research provides essential data for developing evidence-based interventions for children with GDD, improving developmental outcomes.