Related Experiment Video
Updated: Sep 19, 2025

Design of a Biocompatible Drug-Eluting Tracheal Stent in Mice with Laryngotracheal Stenosis
Published on: January 21, 2020
Laryngotracheal mold for stenting in pediatric glottic and subglottic stenosis
Flavia Varela1, Kishore Sandu2
1Department of Otorhinolaryngology, Basel University Hospital USB, Basel, Switzerland.
Objective:
We report the surgical outcomes and functional results in a pediatric population following the use of the laryngotracheal LT-moldR prosthesis to treat complex glottic and subglottic stenosis.
Methods:
A retrospective observational study in children following open and endoscopic surgical treatment for LT stenosis.
Results:
Among 46 patients, 91% received LT-mold during an open surgery and 9% had it following an endoscopic procedure. 93% patients were successfully decannulated and 80% needed stent placement for longer than 2 months. Mean time to decannulation was 229 days. Currently, 83% patients have normal breathing, 67% patients have normal voice or mild dysphonia and swallowing outcomes have remained similar in the pre- and post-operative period.
Conclusion:
The LT-mold provided an adequate airway stenting, enabling decannulation in most patients with advanced grades of laryngotracheal stenosis. Duration of stenting and time to decannulation showed no correlation with the grade of stenosis or patient comorbidities. Functional results were optimal.
Related Concept Videos
Tracheostomy: Procedure and Tubes
Tracheostomy tubes can be made of semiflexible plastic (polyurethane or silicone), rigid plastic, or metal, and they come in...
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques
Trachea
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
Tracheostomy Care II: Procedure
Step 1: Perform hand hygiene, and put on personal protective equipment: gown, gloves, mask...
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Tracheostomy Care I: Pre-procedural Steps
Required Equipment
The equipment necessary for tracheostomy care includes:

