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A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
Published on: February 28, 2013
[Recommendations for the treatment of type 2 diabetes]
1Service de Diabétologie, Nutrition et Maladies métaboliques, CHU Liège, Belgique.
Abstract:
The management of type 2 diabetes relies on an integrated approach that goes beyond metabolic control, also targeting the prevention of cardiovascular and renal complications. Recent guidelines emphasize the importance of a personalized therapeutic strategy, tailored to the individual characteristics of patients, their comorbidities, and based on shared decision-making. SGLT2 inhibitors and GLP-1 receptor agonists have emerged as cornerstone treatments due to their effectiveness in glycaemic control and their demonstrated protective effects on the heart and kidneys. Moreover, weight management is now considered a key therapeutic lever, offering significant metabolic and cardiovascular benefits. Beyond pharmacological choices, therapeutic education, multidisciplinary support, and addressing social determinants of health play a crucial role in optimizing treatment adherence and improving patients' quality of life. A proactive and evolving management approach, adapted to disease progression and individual patient needs, is now at the heart of type 2 diabetes recommendations.
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