Related Experiment Video
Updated: Sep 19, 2025
14:56
Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies
Published on: May 6, 2022
4.7K
EpiWEAT: a new digital assessment tool for epigenetic studies
Marco Giustini1, Anna Carannante1, Duilio Luca Bacocco2
1Dipartimento Ambiente e Salute, Istituto Superiore di Sanità, Rome, Italy.
Annali Dell'Istituto Superiore Di Sanita
|June 16, 2025
Summary
Intimate partner violence (IPV) negatively impacts women's health. A new digital tool assesses IPV contexts, health outcomes, and epigenetic changes, aiding early detection and precision medicine for survivors.
Area of Science:
- Public Health
- Genetics
- Psychology
Background:
- Intimate partner violence (IPV) is linked to chronic diseases in women.
- Epigenetic indicators may reveal long-term trauma effects on the genome.
- Trauma is associated with stress-related conditions like post-traumatic stress disorder (PTSD).
Purpose of the Study:
- To assess the long-term health effects of violence against women.
- To develop a digital tool for collecting comprehensive data on violence, perpetrator-victim dynamics, and health outcomes.
Main Methods:
- A Microsoft Forms questionnaire was created with nine sections.
- The tool includes socio-personal data, violence context, health status, and psychological evaluations.
- PTSD and depression were assessed using validated scales; optional epigenetic analysis via blood samples is included.
Main Results:
- The assessment tool effectively gathers IPV information.
- It evaluates health outcomes and identifies PTSD and depression in survivors.
- Biological samples are collected for epigenetic research.
Conclusions:
- The tool comprehensively assesses IPV, health outcomes, and psychological impact.
- It supports epigenetic research for understanding trauma's genomic effects.
- This instrument can improve interventions, enable precision medicine, and facilitate early risk detection for women experiencing violence.
