Tenosynovial Giant Cell Tumours: A Clinicopathologic Study of a Case-Series

Tenosynovial giant cell tumours (TSGCT) are rare mesenchymal tumours that develop in joints, bursae and tendon sheaths. The aim of this study was to describe the epidemiological, clinical and histopathological aspects of this pathology in Togo.

This was a retrospective descriptive and analytical study of histologically confirmed cases of tenosynovial giant cell tumour from 1 January 2014 to 31 December 2023 in the Pathology Department of the Sylvanus Olympio Teaching Hospital in Lomé, Togo.

We identified 12 cases of tenosynovial giant cell tumours. We found 8 male subjects and 4 female subjects. The mean age of our patients was 24.2 ± 12.8 years. The tumour was located in the fingers in 9 cases (75%) and in the toes in 3 cases (25%). The mean time to diagnosis was 26.3 + 20.8 months. Pain and a palpable mass were the main symptoms. The nodular type was found in 7 cases (58.33%) and the diffuse type in 5 cases (41.67%).

Tenosynovial giant cell tumour is a benign proliferative disorder of the synovium, the aetiopathogenesis of which remains undetermined.