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Artificial Intelligence-Driven Telehealth Framework for Detecting Nystagmus.
Harshal Sanghvi1, Ali A Danesh2, Jillene Moxam3
1Department of Information Technology and Operations Management, College of Business, Florida Atlantic University, Boca Raton, USA.
Cureus
|June 16, 2025
Summary
An AI system for nystagmus detection shows promise for remote diagnosis. This artificial intelligence tool analyzes eye movements, potentially supplementing traditional videonystagmography (VNG) methods.
Area of Science:
- Ophthalmology
- Artificial Intelligence in Medicine
- Medical Diagnostics
Background:
- Nystagmus detection often requires specialized equipment like videonystagmography (VNG).
- Telemedicine offers potential for remote patient care, but requires effective diagnostic tools.
- Integrating AI into clinical workflows can enhance diagnostic capabilities.
Purpose of the Study:
- To implement and evaluate a proof-of-concept AI-driven clinical decision support system for nystagmus detection.
- To assess the system's potential for real-time analysis of clinical data and integration into telemedicine platforms.
- To explore patient benefits including convenience and reduced healthcare costs.
Main Methods:
- A cloud-based deep learning framework was developed to track eye movements and detect facial landmarks in real time.
- The system was trained to analyze data from a bedside clinical test and videonystagmography (VNG).
- Ten subjects participated in this pilot study.
Main Results:
- The AI system's slow-phase velocity (SPV) calculations showed statistical significance (p < 0.05).
- Mean squared error was 0.00459, with a correction error of ±4.8% compared to VNG.
- The system demonstrated accurate real-time eye movement analysis.
Conclusions:
- The deep learning model shows potential for remote diagnostic consultation, possibly supplementing or replacing traditional methods like VNG.
- Advancements in medical AI can improve patient diagnosis, specialist referrals, and physician support.
- Further research with larger sample sizes is warranted for this proof-of-concept study.

