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Updated: Sep 19, 2025

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
Published on: September 20, 2024
A Rare Presentation of Hypocalcaemia-Induced Seizure Secondary to Late-Onset Post-Thyroidectomy Complication
Yameen Hamid1,2, Md Al Amin Sarkar2, Sudip Karmaker2
1Stem Cell and Translational Neurology, University of Edinburgh, Edinburgh, GBR.
Abstract:
We report a rare case of late-onset hypocalcaemia presenting with seizure in a female patient, occurring approximately 25 years after a total thyroidectomy. Initial investigations ruled out intracranial pathology, and biochemical analysis confirmed severe hypocalcaemia. The patient responded to intravenous calcium gluconate infusion, with subsequent stabilisation on oral calcium therapy. Notably, the patient had been non-compliant with long-term calcium supplementation. This report underscores that chronic hypocalcaemia can manifest with acute neurological symptoms such as seizures and highlights the importance of long-term follow-up for post-thyroidectomy patients.
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