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The process of blood cell formation is called hematopoiesis. Hematopoiesis starts early during development, on the seventh day of embryogenesis. This phase of hematopoiesis is called the primitive wave, wherein the extraembryonic yolk sac allows the production of erythroid cells and endothelial cells from a common precursor called hemangioblast. The erythroid cells provide oxygen to support the growth of the rapidly dividing embryo. Hemangioblasts later develop into hematopoietic stem cells or...
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Hematopoiesis, or blood cell production, is a vital biological process that begins early in embryonic development and continues throughout life. This process generates the various types of cells found in blood, including red blood cells, white blood cells, and platelets from hematopoietic stem cells (HSCs).
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All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...
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Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
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Related Experiment Video

Updated: Sep 19, 2025

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management
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Identifying and addressing underuse in hematologic care through systems-based hematology.

Jacob C Cogan1, Allison E Burnett2, Alexandra Power-Hays3,4

  • 1Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, Minnesota, USA.

Research and Practice in Thrombosis and Haemostasis
|June 16, 2025
PubMed
Summary
This summary is machine-generated.

High-value hematologic care is often underused, unlike the overuse of medical treatments. This review highlights key areas for improving patient care through increased utilization of essential hematology interventions.

Keywords:
IVC filteranticoagulationhydroxyureasickle cell anemiaunderuse

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Area of Science:

  • Hematology
  • Health Services Research

Background:

  • Overutilization of medical services often overshadows the underuse of high-value hematologic care.
  • Focusing solely on reducing unnecessary treatments neglects opportunities to improve patient outcomes through essential care.

Purpose of the Study:

  • To analyze the underuse of specific high-value hematologic interventions.
  • To advocate for increased uptake of underutilized hematologic care and systems-based interventions.

Main Methods:

  • Review of underutilized care in procedural (vena cava filter retrieval), medical (hydroxyurea for sickle cell anemia), and patient-facing (anticoagulation education) domains.
  • Identification of systems-based interventions to promote uptake.

Main Results:

  • Identified specific examples of underutilized high-value hematologic care.
  • Demonstrated the need for systems-based approaches to increase the use of these interventions.

Conclusions:

  • Equal attention and investment are needed to promote underused high-value hematologic care, not just reduce overuse.
  • Systems-based interventions are crucial for increasing the uptake of essential hematologic treatments and procedures.