Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

Opioid Analgesics: Synthetic and Semisynthetic Opioids

454
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
454
Opioid Analgesics: Morphine and Other Natural Cogeners01:20

Opioid Analgesics: Morphine and Other Natural Cogeners

382
Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
382
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

859
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
859
Analgesia and Pain Management01:25

Analgesia and Pain Management

823
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
823
Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents01:17

Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents

335
Diarrhea, a condition marked by frequent loose or watery bowel movements, can be triggered by multiple factors such as viral or bacterial infections, food intolerances, anxiety, medications, and digestive disorders. Symptoms may include abdominal pain, bloating, nausea, and cramping. Severe or prolonged diarrhea can lead to complications like electrolyte imbalances, malnutrition, and dehydration if left untreated.
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
335
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

676
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
676

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Feedback, Education, and Protocols to Safely Reduce Emergency Department Admissions for Chest Pain.

Annals of emergency medicine·2026
Same author

Minority Tax in Emergency Medicine Resident Physicians.

AEM education and training·2026
Same author

Retention Challenges in Opioid Use Disorder Treatment: The Role of Comorbid Psychological Conditions.

The western journal of emergency medicine·2026
Same author

IFEM model framework for the accreditation of training sites for emergency medicine specialists.

International journal of emergency medicine·2025
Same author

Retention Challenges in Opioid Use Disorder Treatment: The Role of Comorbid Psychological Conditions.

The western journal of emergency medicine·2025
Same author

The economic burden of hip fractures in the geriatric population by mental health illness and substance Use Status: National estimates 2016 to 2020.

Injury·2025

Related Experiment Video

Updated: Sep 19, 2025

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
10:17

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

9.8K

Emergency Department-Based Medication for Opioid Use Disorder: A 5-Year Experience.

David C Seaberg1, Jamie McKinnon2, Lyn Haselton1

  • 1Department of Emergency Medicine, Summa Health System, Akron, Ohio, USA.

Journal of the American College of Emergency Physicians Open
|June 16, 2025
PubMed
Summary
This summary is machine-generated.

Emergency department Medication for Opioid Use Disorder (MOUD) programs effectively treat opioid use disorder (OUD). However, patient engagement and retention rates declined over five years, necessitating cost-effective strategies for sustained treatment access.

Keywords:
MOUDmedication for opioid use disorderopioid use disordertelehealth

More Related Videos

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
09:29

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods

Published on: August 4, 2022

2.3K
Author Spotlight: An Efficient Methodology to Confidently Differentiate and Characterize Fentanyl Analogs
10:13

Author Spotlight: An Efficient Methodology to Confidently Differentiate and Characterize Fentanyl Analogs

Published on: November 8, 2024

2.4K

Related Experiment Videos

Last Updated: Sep 19, 2025

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
10:17

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

9.8K
Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
09:29

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods

Published on: August 4, 2022

2.3K
Author Spotlight: An Efficient Methodology to Confidently Differentiate and Characterize Fentanyl Analogs
10:13

Author Spotlight: An Efficient Methodology to Confidently Differentiate and Characterize Fentanyl Analogs

Published on: November 8, 2024

2.4K

Area of Science:

  • Emergency Medicine
  • Addiction Medicine
  • Public Health

Background:

  • Medication for Opioid Use Disorder (MOUD) programs are crucial for treating Opioid Use Disorder (OUD).
  • Successful MOUD programs require significant resources.
  • Emergency departments (EDs) are potential access points for MOUD initiation.

Purpose of the Study:

  • To evaluate the 5-year outcomes of an ED-based MOUD program.
  • To assess patient induction numbers, telehealth utilization, and retention rates.
  • To identify trends and factors influencing program effectiveness.

Main Methods:

  • A 5-year retrospective analysis (2019-2023) of an ED-based MOUD program across two hospitals.
  • Screening of all ED patients for OUD.
  • Coordination of care by Addiction Care Coordinators and counseling by peer recovery specialists.
  • Expansion to free-standing EDs via telemedicine in 2021.

Main Results:

  • 1072 out of 373,797 ED patients (2.8%) were inducted into the MOUD program.
  • Telemedicine accounted for 53 inductions (4.9%).
  • Patient induction and 1- and 6-month retention rates (36.5% and 28.8% respectively) showed a yearly decline.

Conclusions:

  • ED-based MOUD programs increase treatment access for OUD patients.
  • Declining patient engagement and retention necessitate further investigation into contributing factors.
  • Development of cost-effective strategies is essential for the long-term sustainability of these vital programs.