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Review on bioactive peptides from Antarctic krill: From preparation to structure-activity relationship and
Zhidong Liu1, Shanshan Wang2, Rong Cao2
1Key Laboratory of Oceanic and Polar Fisheries, Ministry of Agriculture and Rural Affair, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, No. 300 Jungong Road, Yangpu District, Shanghai, 200090, China.
Current Research in Food Science
|June 16, 2025
Summary
Antarctic krill bioactive peptides (AkBPs) offer diverse health benefits, including antioxidant and antimicrobial effects. This review synthesizes research on AkBPs
Area of Science:
- Marine Biotechnology
- Biochemistry
- Food Science
Background:
- Antarctic krill bioactive peptides (AkBPs) are recognized for their abundance, safety, and health benefits.
- These peptides possess a range of bioactivities attributed to their composition and structure.
Purpose of the Study:
- To systematically review the bioactivities, structural characteristics, and functional properties of AkBPs.
- To explore structure-activity relationships and potential applications of AkBPs.
- To identify challenges and future prospects for AkBPs in functional applications.
Main Methods:
- Comprehensive literature search for studies on Antarctic krill bioactive peptides.
- Analysis of research data on peptide bioactivities, structures, and functions.
- Synthesis of findings regarding structure-activity relationships and applications.
Main Results:
- AkBPs demonstrate significant antioxidant, antihypertensive, hepatoprotective, immunoregulatory, antimicrobial, and anti-diabetic effects.
- Peptide properties are influenced by amino acid composition, sequence, conformation, and hydrophilicity/lipophilicity.
- Established structure-activity relationships provide a basis for understanding peptide functionality.
Conclusions:
- AkBPs represent a promising source of bioactive compounds with diverse health-promoting properties.
- Further research into structure-activity relationships can optimize AkBP applications.
- AkBPs hold potential for development as functional food ingredients and therapeutic agents.
Keywords:
Antarctic krillBioactive peptideBioactivityBioavailabilityFunctional propertyStructure-activity relationship
