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Updated: Jul 3, 2026
11:07
Biochemical Reconstitution of Steroid Receptor•Hsp90 Protein Complexes and Reactivation of Ligand Binding
Published on: September 21, 2011
Human lymphocyte glucocorticoid receptors reside mainly in the cytoplasm
Biochemical and Biophysical Research Communications
|September 16, 1985
Abstract:
Karyoplasts prepared from human lymphocytes by treatment with cytochalasin B or lymphocytes permeabilized with digitonin contain only 25-40% of the total cellular glucocorticoid binding activity. The presented results thus support the original concept that unfilled steroid hormone receptors are mainly cytoplasmic.
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