Intelligent soft wearable bioelectronics for neurological disorders

Using soft wearable electronics has emerged as an innovative neurological disorder monitoring and rehabilitation approach. Traditional diagnostic and treatment systems are hospital-centered, bulky, and unsuitable for long-term use, limiting their applicability in real-world settings. Recent advancements in materials, device design, and fabrication processes have enabled the development of stretchable, skin-conformal sensors, improving wearability, signal quality, and usability. This review discusses key design considerations for ensuring conformal integration with the human body, covering aspects from materials selection to structural engineering. Additionally, we explore recent research trends in soft electronics-based electrophysiological and physical activity sensors and the system integration challenges that must be addressed for clinical applications. Finally, we introduce emerging neurological disorder applications utilizing soft wearable electronics, highlighting their limitations and potential. By addressing these challenges, soft wearable electronics will advance continuous health monitoring, personalized rehabilitation, and next-generation neuroprosthetic systems.