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Updated: Sep 19, 2025

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 3
Published on: April 13, 2009
Spatial Transcriptomics to Study Virus-Host Interactions
Chase Holdener1,2, Shaowen Jiang1,2, Danica M Sutherland3,4
1Meinig School of Biomedical Engineering, Cornell University, Ithaca, New York, USA;
Abstract:
The morbidity and mortality associated with viral diseases in plants, animals, and humans are significant concerns. Understanding how viruses cause disease and identifying the viral and host factors that determine the outcome of infection are essential to develop new antiviral therapeutics and strategies to induce protective immunity. In this review, we focus on the transformative potential of spatial transcriptomics for studies of viral pathogenesis and some of the intricacies of corresponding technologies and how to implement them.
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