Changes in cardiorespiratory status after transcatheter patent ductus arteriosus closure

We aim to assess short-term cardiorespiratory outcomes of neonates after transcatheter patent ductus arteriosus (PDA) closure. We hypothesize pre-procedure respiratory severity score (RSS) ≥ 4 is associated with increased risk of post-transcatheter cardiorespiratory syndrome (PTCS).

This was a retrospective study of infants who underwent transcatheter PDA closure from January 2022 to December 2022. Patients were divided by pre-procedure RSS and analyzed for the development of PTCS or hypertensive cardiorespiratory failure.

The study included 46 patients with a mean birthweight of 699 g and procedure weight of 1098 g. PTCS was identified in 5 (11%) patients with no differences based on pre-procedure RSS (8 vs 14%, p = 0.66). Post-procedure hypertension was found in 28 (61%) patients (58 vs 64%, p = 0.77), and occurred with respiratory failure in 12 (26%) patients (33 vs 18%, p = 0.32).

Pre-procedure RSS was not associated with post-procedure outcomes. While PTCS occurred infrequently, post-procedure hypertension was common.