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Updated: Sep 19, 2025

Surgical Treatment of an Endolymphatic Sac Tumor
Published on: May 26, 2023
An Unusual Paraganglioma of the Left Vagus Nerve: A Surgical Conundrum
Antonio Castillo Magaña1, Elias Gallardo-Navarro2, Catalina Gonzalez Aguirre3
1Head and Neck Surgery, Hospital Español, Mexico City, MEX.
Abstract:
Vagus nerve paragangliomas (PGL) are tumors derived from neural crest cells of very low incidence, and cervical PGL of the vagus nerves (VPGLs) are tumors, of which the nature and location make them extremely rare, representing only 0.012% of cervical tumors, with an incidence of 1:30,000-1:200,000. A 76-year-old woman presented with a rapid growth in volume in the left laterocervical region, accompanied by pain for four months. She denied voice changes, difficulty feeding, facial nerve paralysis, headache, hypertension, hearing loss, excessive sweating, tinnitus, and tremors. Catecholamines were requested in blood or urine, which were negative. A computed tomography angiography of the head and neck was performed, where a tumor was identified whose location and characteristics were diagnosed as a PGL of the left vagus nerve; no biopsy was performed. Head and neck surgeons should be aware of large vagal PGL involving nerve or vascular structures, as it is currently difficult to resect the tumor without sacrificing the vagus nerve, and postponing surgery may also increase patient morbidity.
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