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Hypoglycemia and Glucagon

Hypoglycemia and Glucagon

Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...

SBAR II: Application of SBAR

SBAR II: Application of SBAR

SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...

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Related Experiment Video

Updated: Sep 19, 2025

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia

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Hypoglycemic Hemiparesis Presenting as a Stroke Mimic: A Case Report.

Joel Collins¹, James Espinosa¹, James Lee¹

¹Emergency Medicine, Jefferson Health, Stratford, USA.

|June 17, 2025

Summary

Hypoglycemia can mimic stroke symptoms, presenting as hemiparesis and slurred speech. Prompt glucose level assessment is crucial for diagnosing and treating these stroke-like episodes in diabetic patients.

Keywords:

acute hemiplegia due to hypoglycemia hemiparesis due to hypoglycemia hypoglycemic hemiparesis hypoglycemic stroke mimic stroke mimics

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Last Updated: Sep 19, 2025

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Published on: November 15, 2024

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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

Area of Science:

Neurology
Endocrinology
Emergency Medicine

Background:

Diabetes Mellitus (DM) management requires careful monitoring of blood glucose levels.
Stroke-like symptoms necessitate rapid differential diagnosis, including metabolic causes.
Hypoglycemia can manifest with focal neurological deficits, mimicking cerebrovascular events.

Observation:

A 47-year-old male with DM presented with acute right-sided hemiparesis and slurred speech.
Initial blood glucose was critically low (37 mg/dL), with rapid symptom resolution after intravenous dextrose administration.
Cranial imaging (CT head, CT angiogram, MRI brain) revealed no evidence of stroke.

Findings:

The patient's presentation was diagnosed as hypoglycemic hemiplegia, a stroke-like condition caused by severe hypoglycemia.
The etiology was attributed to missed meals and an excessive diabetes medication regimen.
Recurrent hypoglycemia (blood sugar 60 mg/dL) required a second dextrose dose.

Implications:

This case highlights the importance of including blood glucose assessment in stroke protocols.
Early detection and management of hypoglycemia can prevent misdiagnosis and ensure timely treatment.
Understanding hypoglycemia's potential to mimic stroke is vital for emergency department and neurology consultations.