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Global Pattern and Disease Heterogeneity Drivers in Aging Populations
Chengcheng Jin1, Jialian Chen1, Jinqiong Fang1
1The First People's Hospital of Xiaoshan District Xiaoshan Affiliated Hospital of Wenzhou Medical University Zhejiang China.
Geohealth
|June 17, 2025
Summary
Global disease patterns in aging populations show significant geographic and temporal variations. Healthcare strategies must address socio-economic and environmental factors to reduce health disparities in age-related diseases.
Area of Science:
- Gerontology
- Public Health
- Epidemiology
Background:
- Aging populations present complex challenges to global healthcare systems.
- Understanding the diversity of age-related disease prevalence is vital for public health.
- Significant geographic and temporal variations in disease distribution exist among the elderly.
Purpose of the Study:
- To quantify global heterogeneity in the distribution of age-related diseases.
- To analyze trends and influencing factors of disease heterogeneity over time.
- To inform public health strategies for addressing health inequalities in aging populations.
Main Methods:
- Utilized prevalence data for 85 age-related diseases.
- Calculated global disease heterogeneity using the Shannon Diversity Index (SHDI).
- Analyzed geographic, temporal, and demographic variations in SHDI, considering socio-economic and environmental factors.
Main Results:
- Observed significant geographic variations in SHDI, with higher values in high-income Western countries and lower values in South Asia and Oceania.
- SHDI in elderly populations (≥60 years) was higher in Europe and North America compared to Oceania in 2021.
- Global SHDI decreased nonlinearly from 1990 to 2021, with socio-economic factors significantly impacting changes and environmental factors showing gender-specific differences.
Conclusions:
- Geographic and temporal heterogeneity in age-related diseases requires tailored public health interventions.
- Socio-economic and environmental determinants play crucial roles in shaping disease inequalities among the elderly.
- Comprehensive strategies focusing on reducing health disparities and addressing determinants are essential for effective healthcare for aging populations.
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