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Corrigendum to: The Renoprotective and Anti-Inflammatory Effects of Human Urine-Derived Stem Cells on Acute Kidney

Yuanyuan Kuang1,2, Chenyu Fan1,2, Xiaojun Long1,2

  • 1Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.

Current Stem Cell Research & Therapy
|June 17, 2025
PubMed

Insights

Human urine-derived stem cells show renoprotective and anti-inflammatory effects in acute kidney injury (AKI) models. Corrections were made to figures and results, but overall study conclusions remain unaffected.

Area of Science:

  • Nephrology
  • Regenerative Medicine
  • Stem Cell Biology

Background:

  • Acute kidney injury (AKI) is a critical condition with limited therapeutic options.
  • Human urine-derived stem cells (hUSCs) are a promising source for regenerative therapies.
  • Inflammation plays a key role in the pathogenesis of AKI.

Purpose of the Study:

  • To investigate the renoprotective and anti-inflammatory effects of hUSCs in an animal model of AKI.
  • To evaluate the therapeutic potential of hUSCs for kidney injury.

Main Methods:

  • Administration of hUSCs to animals with induced AKI.
  • Assessment of kidney function and histological damage.
  • Analysis of inflammatory markers in kidney tissue.

Main Results:

  • hUSCs demonstrated significant renoprotective effects, improving kidney function.
  • Treatment with hUSCs reduced inflammation in the injured kidneys.
  • Histological analysis showed reduced tissue damage in the hUSCs-treated group.

Conclusions:

  • hUSCs possess significant renoprotective and anti-inflammatory properties relevant to AKI.
  • hUSCs represent a viable therapeutic strategy for managing acute kidney injury.

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