Related Experiment Video
Updated: Sep 19, 2025

10:10
Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
1.5K
Wipe-Out Phenomenon After Gonioscopy-Assisted Transluminal Trabeculotomy.
Enver Mirza1, Gunsu Deniz Mirza2, Mehmet Adam1
1Department of Ophthalmology, Faculty of Medicine, Necmettin Erbakan University.
Journal of Glaucoma
|June 17, 2025
Summary
This case report details a rare instance of vision loss after gonioscopy-assisted transluminal trabeculotomy (GATT) in advanced pseudoexfoliation glaucoma. The wipe-out phenomenon caused irreversible vision loss despite successful intraocular pressure reduction.
Area of Science:
- Ophthalmology
- Glaucoma Surgery
- Surgical Complications
Background:
- Pseudoexfoliation glaucoma is a common cause of secondary glaucoma.
- Advanced glaucoma often requires surgical intervention to preserve vision.
- Gonioscopy-assisted transluminal trabeculotomy (GATT) is an effective MIGS procedure.
Purpose of the Study:
- To report a rare case of the wipe-out phenomenon after GATT.
- To highlight the risk of irreversible vision loss in advanced glaucoma patients undergoing GATT.
Main Methods:
- A 71-year-old male with advanced pseudoexfoliation glaucoma underwent 360-degree GATT.
- Postoperative complications included sudden vision loss and cystoid macular edema (CME).
- Treatment involved anti-inflammatory agents and anti-VEGF injections.
Main Results:
- The patient experienced irreversible vision loss (hand motion) and CME post-GATT.
- Intraocular pressure (IOP) was controlled (11.1 mm Hg) with topical medications.
- CME resolved, but visual acuity did not improve.
Conclusions:
- The wipe-out phenomenon is a potential risk after GATT in advanced glaucoma.
- Careful patient selection is crucial for GATT in advanced glaucoma.
- Ophthalmologists should consider this rare complication when discussing GATT.
Related Concept Videos
Angle Closure Glaucoma: Treatment
718
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
718
Glaucoma: Overview
792
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
792
Open Angle Glaucoma: Treatment
597
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
597

