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Eating disorders in adolescents with functional seizures
Itay Tokatly Latzer1, Tracey Richmond2, Bo Zhang3
1Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA; School of Medicine, Faculty of Medical and Health Sciences, Tel-Aviv University, Tel Aviv, Israel.
Epilepsy & Behavior : E&B
|June 17, 2025
Summary
Eating disorders (EDs) occur in 13.5% of adolescents with functional seizures (FS), often preceding them. Shared risk factors highlight the need for ED screening in FS patients.
Area of Science:
- Child and Adolescent Psychiatry
- Neurology
- Eating Disorders
Background:
- Functional seizures (FS) and eating disorders (EDs) are serious conditions in adolescents.
- The co-occurrence and shared risk factors between FS and EDs require further investigation.
Purpose of the Study:
- To determine the occurrence rate of EDs in adolescents with FS.
- To identify demographic and clinical features associated with the co-occurrence of FS and EDs.
Main Methods:
- An observational, single-centered study over 15 years.
- Included adolescents aged 10-19 with FS and EDs, only FS, or only EDs.
- Utilized group comparison and logistic regression analyses.
Main Results:
- EDs occurred in 13.5% of adolescents with FS, with ED onset preceding FS in 85% of cases.
- Lower zBMI percentile (OR 2.21) increased ED risk.
- Adolescents with FS and EDs showed higher rates of bulimia nervosa, depression, anxiety, substance abuse, trauma history, and suicidality.
Conclusions:
- Shared psychopathology and risk factors link FS and EDs.
- EDs are a significant psychiatric comorbidity in adolescents with FS, warranting screening.
- Individualized treatment plans for FS should consider ED type for improved outcomes.
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