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NICU-specific bundle for minimizing central line-associated bloodstream infections: Comparative health care costs of
Irem Iyigun1, Kubra Aykac2, Pınar Basar3
1Neonatology Unit, Department of Pediatrics, Hacettepe University, Ankara, Turkey.
Background:
Central line-associated bloodstream infections (CLABSIs) in neonatal intensive care units (NICUs) significantly impact patient outcomes and health care costs. This study evaluates the effect of NICU-specific bundle designed to prevent CLABSIs.
Methods:
This retrospective single-center study was conducted at Hacettepe University Faculty of Medicine from March 2020 to August 2021. It was designed to compare 2 periods: pre-intervention and post-intervention period.
Results:
The implementation of the bundles led to a significant reduction in infection rates, with CLABSIs decreasing from 29 to 4 per 1,000 central line days in NICU-1 and from 14.2 to 2.6 per 1,000 central line days in NICU-2. This decline was accompanied by an 80% reduction in the average health care cost per patient.
Conclusions:
The implementation of a NICU-specific CLABSI prevention bundle significantly reduced infection rates and lowered health care costs by approximately 80% per patient. These findings highlight the effectiveness of structured, multidisciplinary infection control strategies in improving neonatal outcomes and resource utilization.
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