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Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
Published on: December 17, 2021
Concurrent hepatitis and anterior uveitis in an immunocompetent patient with secondary syphilis: A case report
Hamed Kheir1, Emad Elazab2, Haytham Hassan1
1Department of Internal Medicine, Al Kharj Military Industries Corporation Hospital, Al Kharj, Saudi Arabia.
Rationale:
Syphilis, a sexually transmitted infection caused by Treponema pallidum, is primarily spread through sexual contact and can lead to severe systemic complications if untreated.
Patient Concerns:
A 42-year-old immunocompetent male presented with a nonpruritic papulosquamous rash sparing the palms and soles, which progressed to anterior uveitis and hepatitis.
Diagnoses:
Diagnosis was confirmed by positive rapid plasma reagin and T pallidum hemagglutination assay, alongside histopathological evidence of granulomatous hepatitis on liver biopsy and slit-lamp findings consistent with anterior uveitis.
Interventions:
The patient was hospitalized and treated with intravenous aqueous penicillin G (3 million units every 4 hours for 14 days).
Outcomes:
To our knowledge, this represents the first reported case in Saudi Arabia of secondary syphilis manifesting concurrently with anterior uveitis and hepatitis in an immunocompetent host.
Lessons:
The study underscores the importance of considering syphilis in atypical presentations to ensure timely diagnosis and management.
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