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Updated: Sep 19, 2025

In Silico Identification and Characterization of circRNAs During Host-Pathogen Interactions
Published on: October 21, 2022
CircRNA Networks in CAD: Multi-Cellular Mechanisms and Clinical Potential
Huan Cheng1, Xinyu Wu2, Jingru Li1
1Department of Cardiology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, 650032, People's Republic of China.
None:
Coronary artery disease (CAD), is a global cardiovascular disease that is characterized by myocardial ischemia and hypoxia caused by coronary artery occlusion. Circular RNAs (CircRNAs) is a particular kind of endogenous non-coding RNA, which can affect the occurrence and development of CAD. Concurrently, several circRNAs display stable persistence in CAD patients, attributable to their exceptional exonuclease resistance, thereby harboring the capacity to evolve into a biomarker for CAD diagnosis and prognosis. This article endeavors to clarify the pivotal role of circRNAs in the intricate pathophysiological processes underlying CAD patients or CAD disease models based on their unique biological characteristics and functionalities, and further discuss their prospects in clinical applications of CAD.
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Protein Networks
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
lncRNA - Long Non-coding RNAs

