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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Related Experiment Video

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Choroidal changes after vitrectomy performed for macular hole retinal detachment.

Hirotaka Sumida1, Ikuko Umeda1, Takayuki Baba2

  • 1Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, 260-0856, Japan.

Japanese Journal of Ophthalmology
|June 18, 2025
PubMed
Summary

Vitrectomy for macular hole retinal detachment causes choroidal thinning, primarily due to reduced luminal area. This study tracked changes in choroidal vascularity and thickness post-surgery.

Keywords:
Choroidal thicknessHigh myopiaMacular hole retinal detachmentOptical coherence tomographyVitrectomy

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Area of Science:

  • Ophthalmology
  • Retinal Surgery
  • Choroidal Imaging

Background:

  • Macular hole retinal detachment (MHRD) poses a significant challenge in retinal surgery.
  • Understanding the impact of vitrectomy on choroidal vasculature is crucial for patient outcomes.

Purpose of the Study:

  • To investigate changes in choroidal area (CA), luminal area (LA), stromal area (SA), choroidal vascularity index (CVI), and choroidal thickness (CT) after vitrectomy in MHRD eyes.
  • To assess the correlation between these parameters and visual acuity outcomes.

Main Methods:

  • A retrospective observational study involving 10 eyes with MHRD.
  • Preoperative and postoperative measurements (1, 3, and 6 months) of BCVA, IOP, CA, LA, SA, CVI, and CT.
  • Quantitative analysis of choroidal parameters using the Niblack method and specific measurement protocols.

Main Results:

  • Significant improvement in best-corrected visual acuity (BCVA) was observed at 1 and 3 months post-vitrectomy.
  • Choroidal area (CA) and luminal area (LA) significantly decreased by 6 months.
  • Choroidal thickness (CT) showed significant reductions, particularly in the subfoveal region and surrounding areas, starting from 1 month postoperatively.

Conclusions:

  • Vitrectomy in MHRD eyes leads to significant choroidal thinning.
  • The reduction in choroidal thickness is primarily attributed to a decrease in the luminal area, indicating vascular remodeling.
  • These findings highlight the anatomical changes in the choroid following MHRD surgery.