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Evaluation of local and systemic photobiomodulation in only single-implant insertion: a randomized clinical trial
Daniel Sartorelli Pucca1, Sérgio Luiz Pinheiro2
1Program in Health Sciences, School of Life Sciences, Postgraduate Program in Health Sciences, Pontifícia Universidade Católica de Campinas (PUC Campinas), Campinas, SP, Brazil.
Objectives:
To evaluate the effects of local and systemic photobiomodulation (PBM-T) after dental surgery for single-tooth implant placement in healed sites.
Materials And Methods:
Fifty-one patients were included and randomly assigned to 2 groups: PBM-T (n = 26), with local and systemic PBM-T application immediately after implant site drilling and suturing; and control group (n = 25), with PBM-T simulation. The parameters used for local PBM-T were low-intensity laser diode (Therapy EC, DMC, São Carlos, SP, Brazil), 1 J of energy per point for 10 s, energy density of 10.20 J/cm², output spot of 0.09842 cm², infrared wavelength of 808 nm and power of 100 mW/cm². Systemic PBM-T was performed using the same low-intensity laser diode. Patients received a single 10-minute systemic transdermal irradiation over the radial artery immediately after suturing, with a total energy of 60 J, energy density of 306.12 J/cm², wavelength of 660 nm, and power of 100 mW. Postoperative pain via visual analog scale (VAS), analgesic use, healing, and quality of life using the Oral Health Impact Profile (OHIP-14) were assessed. Results were analyzed using the Kruskal-Wallis test (Student-Newman-Keuls) and chi-square test.
Results:
There was no significant difference in VAS pain scores between the control and PBM-T groups (p = 0.5217). The number of analgesics taken by participants in the control group was 2.37 times higher than that taken by the PBM-T group. A significant difference in healing grades was observed between the control and PBM-T groups at both the 3-day and 7-day assessments (p = 0.0029 and p = 0.0002, respectively), with the PBM-T group demonstrating marked improvement. There was no negative impact on quality of life at any point after implant placement in the PBM-T group, as all OHIP-14 scores remained lower than those obtained before surgery.
Conclusions:
The combined use of local and systemic PBM-T decreased the need for postoperative analgesics, enhanced postoperative healing, and improved quality of life for patients undergoing single-tooth implant placement in healed sites.
Clinical Relevance:
The clinical application of systemic PBM-T enhances the effects of local PBM-T after dental surgery for implant placement.
Trial Registration Number:
Brazilian Registry of Clinical Trials (ReBEC), with the identifier RBR-7f42fs5, on Nov 30, 2023.
