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Updated: Sep 19, 2025

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Emerging Trends in Point-of-Care Technology Development for Oncology in Low- and Middle-Income Countries.

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  • 1Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY.

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Innovative point-of-care technologies (POCTs) are crucial for improving cancer diagnostics in low-resource settings. Addressing infrastructure challenges through partnerships can enhance accessibility and reduce global disparities in cancer care.

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Area of Science:

  • Oncology
  • Medical Diagnostics
  • Global Health

Background:

  • Growing global cancer burden, particularly in low- and middle-income countries (LMICs).
  • Suboptimal diagnostic capacity in resource-constrained settings necessitates innovative solutions.
  • Need for accessible, rapid, and affordable cancer diagnostic tools.

Purpose of the Study:

  • To review recent advancements in point-of-care technologies (POCTs) for oncology.
  • To examine how public-private partnerships and collaborations can overcome implementation barriers for POCTs in LMICs.
  • To discuss the potential of POCTs to reduce global disparities in cancer diagnosis and treatment.

Main Methods:

  • Review of recent scientific literature on POCTs for cancer diagnostics.
  • Analysis of emerging technologies like loop-mediated isothermal amplification, multiplexed lateral flow immunoassays, optical coherence tomography, and fluorescence-guided microscopy.
  • Examination of the role of artificial intelligence in enhancing diagnostic accuracy.
  • Assessment of infrastructure and logistical challenges in POCT implementation.
  • Exploration of strategies involving public-private partnerships and multisector collaborations.

Main Results:

  • POCTs enable high-sensitivity biomarker detection without complex labs.
  • Noninvasive imaging tools offer portable, cost-effective early detection solutions.
  • Artificial intelligence integration improves accuracy and reduces personnel dependency.
  • Persistent challenges include resource constraints, unreliable power, and cold-chain limitations.
  • Public-private partnerships are key to addressing implementation barriers.

Conclusions:

  • POCTs represent a transformative approach to decentralizing cancer diagnostics.
  • Overcoming infrastructure and logistical hurdles is critical for widespread POCT adoption.
  • Inclusivity, cross-sector collaboration, and targeted investments can sustainably reduce global cancer diagnostic disparities.