In Defense of Biochemistry: Studies of Transcriptional Regulation

Roger D Kornberg1, Andrey Feklistov1

  • 1Department of Structural Biology, Stanford University, School of Medicine, Stanford, CA 94305, United States.

PubMed

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Transcription

Transcription is the synthesis of RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in correctly synthesizing messenger RNA (mRNA). Transcriptional regulation is responsible for the differentiation of different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds of RNA Molecules
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