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Compost Microcosms as Microbially Diverse, Natural-like Environments for Microbiome Research in Caenorhabditis elegans
Published on: September 13, 2022
Large-scale microbiome data initiatives call for diversity
Quin Yuhui Xie1, Jayne S Danska2
1Department of Medical Biophysics, University of Toronto, Toronto, M5T2S8, Canada; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, M5G1X8, Canada.
Abstract:
High variability in human gut microbiota is a challenge in the identification of consistent microbe-disease associations. Two Cell papers by Nishijima et al. and Abdill, Graham, et al. addressed this by curating large public microbiome datasets. They highlight long overlooked drivers of gut microbiome variance, such as fecal microbial biomass and geographical locations of study participants, necessitating diverse population representation in microbiome research.
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