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Updated: Sep 19, 2025
09:20
Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
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iCARDIO Alliance Global Implementation Guidelines on Heart Failure 2025.
Heart, Lung & Circulation
|June 18, 2025
Summary
Global heart failure (HF) guidelines are updated to address worldwide challenges, incorporating novel therapies and evidence-based care. Recommendations include economic adjustments for limited resources, aiming to improve patient outcomes globally.
Area of Science:
- Cardiology
- Global Health
- Evidence-Based Medicine
Background:
- Current heart failure (HF) guidelines face limitations in global applicability due to healthcare inconsistencies, resource constraints, and diverse practices.
- There is a critical need for universal recommendations addressing worldwide challenges in HF patient care and clinical practice.
Purpose of the Study:
- To present the iCARDIO Alliance Global Implementation Guidelines for heart failure (HF) management.
- To integrate novel therapies and current evidence into a unified strategy applicable globally, considering resource limitations.
Main Methods:
- Development of evidence-based recommendations through group consensus, considering existing guidelines and recent evidence.
- Inclusion of context-specific recommendations tailored to individual patient needs and resource availability ('economic adjustments').
- Comprehensive review of pharmacological, non-pharmacological, invasive, and interventional management strategies for HF.
Main Results:
- The guidelines offer a unified strategy for HF management, applicable across diverse global healthcare settings.
- Specific recommendations address resource limitations, providing guidance for 'somewhat limited' and 'severely limited' resource scenarios.
- Emphasis on optimizing patient care by incorporating novel therapies and the latest evidence for acute/chronic HF, HF with reduced/preserved ejection fraction, and cardiomyopathies.
Conclusions:
- These global HF guidelines provide a comprehensive and concise update, aiming to standardize care and improve patient outcomes worldwide.
- The guidelines empower clinicians to optimize HF management by evaluating risks, benefits, and value of therapies, even in resource-constrained environments.
- Implementation of these guidelines is expected to reduce hospitalizations and the overall burden of heart failure as a global health challenge.
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