Level of plasma fibronectin in patients with peripheral vascular disease

Plasma concentration of fibronectin, a recently characterized high molecular mass glycoprotein, was determined in patients with peripheral vascular disease. The plasma fibronectin concentration was lower in patients with peripheral obstructive arterial disease as well as in patients with venous disease, than in corresponding healthy controls. Patients with venous disease had significantly lower levels of plasma fibronectin than patients with peripheral obstructive arterial disease. The patients with peripheral arterial disease were divided into two groups, one having diabetes and another not having diabetes respectively. Between these two groups there was no significant difference in plasma fibronectin concentration.