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Chronic non-healing ulcer reveals pyoderma gangrenosum: A case report
Orhan Yilmaz1, Philip Doiron2, Robyn Evans3
1College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
SAGE Open Medical Case Reports
|June 19, 2025
Summary
Pyoderma gangrenosum, a rare skin condition, presents diagnostic and treatment challenges, especially without systemic links. This case details managing a chronic ulcer unresponsive to initial therapies, underscoring individualized, multidisciplinary care.
Area of Science:
- Dermatology
- Clinical Case Study
Background:
- Pyoderma gangrenosum (PG) is a rare, ulcerative neutrophilic dermatosis.
- Diagnosis can be challenging, often requiring exclusion of other conditions.
- Management is complex, particularly in idiopathic cases.
Observation:
- A 71-year-old female presented with a chronic, non-healing leg ulcer.
- Initial treatments with conventional topical therapies were ineffective.
- Biopsy confirmed the diagnosis of pyoderma gangrenosum.
Findings:
- Treatment involved intralesional and topical therapies.
- Variable responses to different treatment modalities were observed.
- The case underscores the difficulty in managing recalcitrant PG ulcers.
Implications:
- Highlights diagnostic and therapeutic complexities of pyoderma gangrenosum.
- Emphasizes the need for a high index of suspicion for PG in non-healing ulcers.
- Stresses the importance of individualized, multidisciplinary management for optimal outcomes.
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