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Updated: Sep 19, 2025
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Dataset on quantitative behavioral and EEG of lateral cerebellar nucleus (LCN) electrical stimulation in PTZ-kindled
Leonid S Godlevsky1, Mykhailo P Pervak2, Olha S Yehorenko2
1Department of Physiology and Biophysics, Odesa National Medical University, Valikhovsky Lane 2, Odesa, 65082, Ukraine.
Abstract:
The data represented here are in relation to the manuscript (Godlevsky et al., 2025) [1], which quantitatively estimated the effects of the lateral cerebellar nucleus (LCN) electrical stimulation (100 Hz) in rats kindled with pentylenetetrazol (PTZ) daily administration. Both behavioral Racine scale scoring seizure severity and EEG seizure discharges registered in the frontal cortex of rats kindled to the early stage of kindling (not exceeded 2 scored seizure severity) after 9-11 PTZ, and fully developed kindling (4-5 scored seizure severity) after 21 PTZ were quantitatively analyzed. The data in the Tables favors the contribution of LCN to the dynamic of behavioral and EEG seizures, namely, the facilitation of myoclonic seizures at an early stage and the prevention of generalized seizures at the stage of kindled tonic-clonic seizures. Accordingly, all results are presented in primary individual form and quantitatively analyzed, which might better understand LCN's role in the pathogenesis of chronic epileptic syndrome.
