Related Experiment Video

Updated: Sep 19, 2025

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq
07:09

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq

Published on: May 28, 2021

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The role of MYEOV gene: a review and future directions

Yidan Xi1, Xuefei Liu1, Yanan Ge1

  • 1Department of Oncology, General Hospital of Northern Theater Command, Shenyang, China.

Frontiers in Oncology
|June 19, 2025
PubMed

Insights

The overexpressed gene MYEOV functions as an oncogene in multiple cancers, including multiple myeloma. This review covers MYEOV

Area of Science:

  • Oncology
  • Molecular Biology
  • Cancer Genetics

Background:

  • The MYEOV gene is frequently overexpressed in various cancers, acting as an oncogene.
  • MYEOV is implicated in multiple malignancies, including multiple myeloma, breast cancer, lung cancer, pancreatic cancer, and esophageal cancer.
  • While MYEOV has an open reading frame in primates, direct evidence of its functional protein is limited.

Purpose of the Study:

  • To comprehensively review the role of the MYEOV oncogene in tumor development.
  • To explore MYEOV's involvement in cancer cell signaling pathways and miRNA regulatory networks.
  • To discuss recent advancements in MYEOV-targeted cancer therapies.

Main Methods:

  • Literature review of studies on MYEOV expression and function in cancer.
  • Analysis of MYEOV's role in oncogenesis, signaling pathways, and miRNA interactions.
  • Examination of current and emerging therapeutic strategies targeting MYEOV.

Main Results:

  • MYEOV's oncogenic activity is linked to its high expression in tumors.
  • MYEOV influences tumor cell signaling and acts as a competing endogenous RNA (ceRNA).
  • MYEOV may regulate cancer-related genes via enhancer activity.

Conclusions:

  • MYEOV is a significant oncogene with a multifaceted role in cancer progression.
  • Understanding MYEOV's mechanisms is crucial for developing effective cancer treatments.
  • Targeted therapies against MYEOV show promise for managing various malignancies.
Keywords:
MYEOVbiomarker therapysignaling pathwaytargettumor

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