Related Experiment Video
Updated: May 4, 2026

Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites
Published on: November 9, 2014
Allergic Contact Dermatitis From Dental Bonding Materials Containing Methacrylate: A Report of Two Cases
Abdulaziz Aljohani1, Asma Aloufi1, Ahmad A Qazali2
1College of Dentistry, Taibah University, Medina, SAU.
Abstract:
Dental practitioners face occupational hazards, including allergic contact dermatitis (ACD) from materials like methacrylates found in dental bonding agents. ACD is a localized immune reaction causing dry skin, eczema, and sores. Despite using gloves, these chemicals can penetrate and cause skin reactions. The presented cases are of two dental practitioners who complained of signs and symptoms of ACD on the skin of their hands following regular restorative procedures. Later on, these complaints were diagnosed as ACD. The two male dentists developed ACD on the dorsal side of their hands due to improper handling of bonding materials. The allergens had penetrated despite using gloves, leading to localized rashes and itching. Diagnosed as a delayed type IV hypersensitivity reaction, both cases resolved with corticosteroids and improved handling. The exposure to methacrylate-containing dental bonding agents during routine procedures has the potential to develop ACD through direct or indirect skin contact. Increasing the awareness of the potential risks of methacrylate on the skin would consequently improve material handling techniques and identify appropriate methods for intervention and treatment in case the substance causes any adverse effects.
Related Concept Videos
Allergic Reactions
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Allergic Drug Reactions
Local Anesthetics: Differential Sensitivity of Nerve Fibers
Drug Toxicity: Allergic Reactions
Staphylococcal Skin Infections

