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Interventions for cognitive frailty: developing a Delphi consensus with multidisciplinary and multisectoral experts.

Carol A Holland1,2, Nikolett Dravecz1,2, Susan Broughton1,3

  • 1Centre for Ageing Research (C4AR), Lancaster University, Lancaster, United Kingdom.

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|June 19, 2025
PubMed
Summary
This summary is machine-generated.

This study established consensus on interventions for Cognitive Frailty (CF), a condition combining physical frailty and cognitive impairment. The findings will inform public health policies and co-create evidence-based prevention and intervention plans for older adults.

Keywords:
Delphi studycognitive frailty (CF)expert consensusinterventionmulti-sectoralmultidisciplinary

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Area of Science:

  • Gerontology
  • Neuroscience
  • Public Health

Background:

  • Cognitive Frailty (CF) is the conjunction of physical frailty and cognitive impairment without dementia.
  • CF is potentially reversible, suggesting risk factors and symptoms are targets for intervention.
  • Previous interventions lacked multi-sectoral expert input, often focusing solely on academic or clinical perspectives.

Purpose of the Study:

  • To achieve international Delphi consensus on targets, content, and modes of interventions for Cognitive Frailty.
  • To integrate perspectives from diverse stakeholders, including researchers, people with lived experience, carers, and clinicians.
  • To lay the groundwork for evidence-based prevention and intervention strategies for CF.

Main Methods:

  • An international Delphi consensus study involving multiple rounds of surveys.
  • Scoping review and initial statement gathering followed by quantitative and qualitative analysis of participant responses.
  • Inclusion of diverse participants: academic/clinical researchers, people with lived experience, informal carers, and professional care practitioners.

Main Results:

  • Consensus was reached on 89 out of 90 statements regarding CF interventions.
  • Quantitative analysis yielded 74 statements with at least 70% agreement, supplemented by 24 qualitative statements.
  • Minor differences in views were observed between expert groups.

Conclusions:

  • The consensus provides a foundational step for defining health promotion and intervention activities for CF.
  • Findings represent inter-sectoral expert opinion to inform public health policies for CF prevention and management.
  • The study emphasizes stakeholder inclusion for co-creating effective interventions for Cognitive Frailty.