Non-linear relationship between calf circumference and global cognition in Chinese population: a cross-sectional study of 12,102 Chinese older adults
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View abstract on PubMed
Summary
This summary is machine-generated.Calf circumference (CC) is linked to cognitive function in older Chinese adults, with a non-linear relationship observed. This association differs by sex, highlighting potential interventions for women with lower calf circumference to support cognitive health.
Area Of Science
- Gerontology
- Cognitive Neuroscience
- Public Health
Background
- Limited research exists on calf circumference (CC) and global cognition in Chinese older adults.
- Potential sex disparities in this relationship are underexplored.
Purpose Of The Study
- To investigate the correlation between calf circumference (CC) and global cognition in the Chinese population.
- To specifically examine sex variations in the CC-cognition relationship.
Main Methods
- Utilized data from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) 2018.
- Employed multiple linear regression and smoothed curve fitting for association analysis.
- Conducted subgroup analyses to assess the reliability of findings.
Main Results
- A positive correlation was found between global cognition and CC (β = 0.42, P < 0.001).
- A non-linear relationship was identified, with an inflection point at 31 cm for the overall population.
- Sex-specific differences emerged: a non-linear link in women (inflection point 32 cm) but not in men.
Conclusions
- Calf circumference exhibits a non-linear association with global cognition in older Chinese adults.
- Significant sex disparities exist, with women showing a non-linear relationship.
- Older women with lower CC may benefit from physical activity to maintain cognitive function.
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