Chlamydia and Perihepatitis (Fitz-Hugh-Curtis Syndrome) in an 18-Year-Old Male: A Case Report

Anup H Kotadia1, Kenneth Raney1

  • 1Internal Medicine, Methodist Health System, Dallas, USA.

Cureus
|June 19, 2025
PubMed

Insights

Perihepatitis, a liver capsule inflammation, is typically seen in women. This case highlights a rare instance in an 18-year-old male with Chlamydia trachomatis, emphasizing the need to consider similar diagnoses in males.

Area of Science:

  • Hepatology
  • Infectious Diseases
  • Gastroenterology

Background:

  • Perihepatitis, inflammation of the liver capsule, is a known complication of pelvic inflammatory disease (PID).
  • It typically affects women and can lead to significant intraabdominal adhesions and complications.
  • This condition involves inflammation extending to the surface of the liver, often associated with upper abdominal pain.

Observation:

  • An 18-year-old male presented with a three-month history of abdominal pain.
  • Initial diagnosis upon admission was peritonitis.
  • Imaging studies revealed extraluminal air within the liver vasculature, a critical finding.

Findings:

  • The patient tested positive for *Chlamydia trachomatis*.
  • This led to a confirmed diagnosis of chlamydia infection.
  • The clinical presentation and diagnostic findings were consistent with perihepatitis in a male patient.

Implications:

  • This case underscores the importance of recognizing pelvic inflammatory disease-like intraabdominal infections in males.
  • Chlamydia can cause serious intraabdominal complications in men, not just women.
  • Early diagnosis and treatment are crucial to prevent potential lifelong intraabdominal complications.

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