Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Variation in cutaneous sensation between synthetic pyrethroid insecticides.

S A Flannigan, S B Tucker

    Contact Dermatitis
    |September 1, 1985
    PubMed
    Summary

    Synthetic pyrethroids cause skin sensations like paresthesia. This study found differences in paresthesia among pyrethroids and validated dl-alpha tocopheryl acetate as a treatment for skin exposure.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Novel homozygous nonsense TMC8 mutation detected in patients with epidermodysplasia verruciformis from a Brazilian family.

    The British journal of dermatology·2007
    Same author

    Expression of Hras-p21 and keratin K13 in UVR-induced skin tumors in Sencar mice.

    Journal of toxicology and environmental health. Part A·1998
    Same author

    Chronic ultraviolet exposure-induced p53 gene alterations in Sencar mouse skin carcinogenesis model.

    Journal of toxicology and environmental health·1997
    Same author

    Normal mouse skin lymphocyte, Langerhans cell, and keratinocyte responses to intradermal injections of interferon-alpha and interferon-gamma.

    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research·1995
    Same author

    A case study of dermatitis based on a collaborative approach between occupational physicians and industrial hygienists.

    American Industrial Hygiene Association journal·1995
    Same author

    Sweet syndrome in patients with solid tumors.

    Cancer·1993

    Area of Science:

    • Toxicology
    • Dermatology
    • Environmental Science

    Background:

    • Synthetic pyrethroids are widely used insecticides for agriculture and public health.
    • Insecticide resistance is a growing concern, driving research into alternative applications like ultra-low volumes.
    • Cutaneous paresthesia is a common adverse effect of topical exposure to synthetic pyrethroids.

    Purpose of the Study:

    • To investigate and compare the degree of paresthesia induced by different formulations of synthetic pyrethroids.
    • To evaluate the efficacy of dl-alpha tocopheryl acetate in mitigating pyrethroid-induced cutaneous paresthesia.

    Main Methods:

    • Comparative analysis of paresthesia severity following topical application of four distinct synthetic pyrethroid formulations.
    • Statistical validation of dl-alpha tocopheryl acetate as a therapeutic intervention.

    Main Results:

    • Significant variations in the intensity of paresthesia were observed among the tested synthetic pyrethroid formulations.
    • Dl-alpha tocopheryl acetate demonstrated statistically significant efficacy in alleviating cutaneous symptoms after pyrethroid exposure.

    Conclusions:

    • Formulation plays a critical role in the pyrethroid-induced paresthesia response.
    • Dl-alpha tocopheryl acetate is a validated and effective treatment for managing skin irritation caused by synthetic pyrethroids.

    Related Experiment Videos