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Temporal trends in mortality due to coronary heart disease in Germany from 1998 to 2023
Henriette Steppuhn1, Jens Baumert1, Viktoria Rücker2
1Robert Koch Institute, Department for Epidemiology and Health Monitoring, Berlin, Germany.
Insights
Coronary heart disease (CHD) mortality decreased significantly in Germany from 1998-2023, but the trend has flattened since the 2010s, especially for middle-aged adults and chronic CHD mortality in men.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Coronary heart disease (CHD) is a leading cause of death in Germany.
- Comprehensive long-term CHD mortality trend analyses distinguishing between acute myocardial infarction (AMI) and chronic CHD are lacking.
Purpose of the Study:
- To analyze long-term trends in CHD mortality in Germany from 1998 to 2023.
- To differentiate trends between AMI and non-AMI-related chronic CHD.
- To identify potential unmet needs in prevention strategies.
Main Methods:
- Utilized German cause-of-death statistics (1998-2023).
- Calculated age-specific and age-standardized CHD mortality rates.
- Employed joinpoint regression analysis to estimate annual and average annual percentage changes.
Main Results:
- Age-standardized CHD mortality rates declined annually by -3.9% for women and -3.2% for men.
- The downward trend in CHD mortality has flattened since the 2010s, particularly in the 60-74 age group.
- Mortality rates for chronic CHD declined less sharply than for AMI, especially in men.
Conclusions:
- The observed flattening of CHD mortality trends, particularly in middle-aged adults and for chronic CHD in men, warrants further investigation.
- Identifying unmet needs at various prevention levels for specific life stages is crucial.
- The impact of the COVID-19 pandemic on CHD mortality trends requires further study.
Background:
Coronary heart disease (CHD) is the leading cause of death in Germany. Comprehensive analyses of long-term trends in CHD mortality that also distinguish between acute myocardial infarction (AMI) and non-AMI-related chronic CHD are currently lacking.
Method:
Age-specific and age-standardised CHD mortality rates for the period 1998 - 2023 were calculated based on data from the cause-of-death statistics of the Federal Statistical Office of Germany. Annual percentage changes (APC) and average annual percentage changes (AAPC) were estimated using joinpoint regression analysis.
Results:
Between 1998 and 2023, the average annual change in age-standardised CHD mortality rates for women was -3.9 % ((-4.1) - (-3.7)) per year, compared with -3.2 % ((-3.3) - (-3.0)) for men. However, since the 2010s, the downward trend in CHD mortality has flattened, particularly among those aged 60 to 74 years. In the analysis by ICD subgroups, mortality rates for chronic CHD declined less sharply than for AMI over the entire period 1998 - 2023, especially among men.
Conclusions:
The flattening of the CHD mortality trend, particularly among middle-aged adults over the last decade, and the smaller decline in chronic CHD mortality, especially among men, require further exploration in order to identify unmet needs at various levels of prevention for specific life stages. In addition, the influence of the COVID-19 pandemic on CHD mortality trends should be further investigated.
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