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Effect of Indirect Pulp Capping Materials On Regional Dentin Seal
The Journal of Adhesive Dentistry
|June 19, 2025
Summary
Indirect pulp capping (IPC) materials, except Kerr Life, do not negatively impact dentin bond strength in deep cavities. Hydraulic cements are safe for peripheral dentin seal.
Area of Science:
- Dentistry
- Dental Materials Science
- Adhesive Dentistry
Background:
- Indirect pulp capping (IPC) is a vital dental procedure to preserve pulp vitality.
- Evaluating the impact of IPC materials on the integrity of the dentin-tooth structure is crucial for long-term restoration success.
- Understanding the influence of various IPC agents on the bond strength to dentin is essential for clinical decision-making.
Purpose of the Study:
- To assess the in-vitro effect of six different indirect pulp capping materials on the micro-tensile bond strength (µ-TBS) to surrounding dentin.
- To determine if IPC materials compromise the peripheral seal of adhesive restorations.
- To compare the performance of Kerr Life (KL), Dycal (DY), Theracal LC (TC), Calcimol LC (CL), Biodentine (BD), and ProRoot MTA (PR).
Main Methods:
- Fifty-six human third molars were used, with occlusal dentin exposed in 42 teeth.
- IPC materials were applied centrally, followed by bonding with Scotchbond Universal and composite resin restoration.
- Micro-tensile bond strength (µ-TBS) testing was performed at different distances from the IPC, with fracture analysis and SEM imaging.
Main Results:
- A significant reduction in peripheral seal was observed only for Kerr Life (KL).
- All tested IPC materials demonstrated increasing bond strengths from the central application area towards the periphery.
- These findings suggest a potential contamination effect of IPC materials on the surrounding dentin interface.
Conclusions:
- Indirect pulp capping materials, excluding Kerr Life, do not compromise the peripheral dentin seal when used in deep cavity preparations.
- Hydraulic cements, such as Biodentine and Theracal LC, can be utilized without adverse effects on the peripheral dentin seal.
- The study highlights the importance of material selection in indirect pulp capping to maintain restoration integrity.

