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MRD and NK-Cell Chimerism Predict Transplant Outcomes in Allogeneic Hematopoietic Stem Cell Transplantation

Xing Chen1, Huihong Huang2,3, Weihao Chen4

  • 1Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

American Journal of Hematology
|June 19, 2025
PubMed

Keywords:
NK cellsallogeneic hematopoietic stem cell transplantationdonor chimerismmeasurable residual diseaserelapse

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
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