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Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
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Updated: Sep 19, 2025

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Splenic Injuries Due to Colonoscopy in Adult Out-Patients-A Registry-Based Study.

Herbert Koop1, Christoph Skupnik2, Torsten Schnoor3

  • 1Formerly Department of Medicine and Gastroenterology, Campus Medical School Berlin, Helios Klinikum Berlin-Buch, Toelzer Str. 20, 14199, Berlin, Germany. prof.koop@t-online.de.

Digestive Diseases and Sciences
|June 19, 2025
PubMed
Summary
This summary is machine-generated.

Splenic injuries from colonoscopy are rare, occurring in about 1 in 31,400 outpatients. While less common than in hospitalized patients, endoscopists should remain vigilant for this serious complication.

Keywords:
Endoscopy complicationsEpidemiologySplenectomy

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Area of Science:

  • Gastroenterology
  • Surgical Complications
  • Public Health

Background:

  • Splenic injuries post-colonoscopy are poorly understood, with potentially significant incidence in hospitalized patients.
  • The risk for outpatients undergoing colonoscopy is less clear.

Purpose of the Study:

  • To determine the incidence, risk factors, and outcomes of splenic lesions following outpatient colonoscopy.
  • To analyze a large cohort of over 1.44 million outpatient colonoscopies.

Main Methods:

  • Utilized an administrative database from a health insurance company covering 11 million individuals.
  • Identified 163 cases of splenic injury within 7 days of colonoscopy using specific diagnostic codes.
  • Excluded cases with other causes of splenic injury, reconstructing clinical courses for identified patients.

Main Results:

  • Identified 46 splenic lesions likely caused by colonoscopy in 1,443,341 procedures (3.19 per 100,000).
  • Females had a higher relative risk (1.7) of injury. 41% required surgery (17 splenectomies), while 59% were managed conservatively.
  • Transfusions and intensive care predicted surgical need; 63% of lesions were diagnosed within 48 hours.

Conclusions:

  • Splenic injuries from outpatient colonoscopy appear less frequent than in hospitalized patients.
  • Endoscopists must be aware of this rare but potentially life-threatening adverse event.
  • Further awareness and vigilance are recommended for clinicians performing colonoscopies.