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Related Concept Videos

Brain Imaging01:14

Brain Imaging

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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
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Interoceptive Dysfunction in Psychiatric Disorders and Non-invasive Neuromodulation for Improving Interoception.

Huiru Cui1, Jijun Wang2,3, Chunbo Li2,4

  • 1Neuromodulation Center, Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China. cuihuiru@163.com.

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|June 19, 2025
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Interoceptive system dysfunction is linked to mental health disorders. Non-invasive neuromodulation offers a promising approach to regulate interoception and treat these conditions, with ongoing research exploring its mechanisms and applications.

Keywords:
InsulaInteroceptionNeuromodulationPerceptionPsychiatric disorders

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Clinical Psychology

Background:

  • Interoceptive system dysfunction is implicated in various mental health conditions such as anxiety, depression, and psychosis.
  • Non-invasive neuromodulation is an emerging therapeutic strategy for psychiatric disorders.

Purpose of the Study:

  • To review the pathways and assessment methods of interoception.
  • To summarize interoceptive abnormalities in psychiatric disorders.
  • To examine current non-invasive neuromodulation strategies targeting interoception.

Main Methods:

  • Literature review of interoceptive pathways, assessment tools, and neuromodulation studies.
  • Analysis of interoceptive abnormalities in psychiatric disorders.
  • Synthesis of findings on neuromodulation interventions, including modes, targets, and mechanisms.

Main Results:

  • Dysfunctional interoception is a common feature across multiple psychiatric disorders.
  • Non-invasive neuromodulation techniques show potential for regulating interoception.
  • Research is exploring various intervention targets and neurobiological mechanisms.

Conclusions:

  • Targeting the interoceptive system with non-invasive neuromodulation presents a novel therapeutic avenue for mental health disorders.
  • Further research is needed to address current challenges and optimize treatment strategies.