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Prevalence of cardiac dysfunction in men with erectile dysfunction: the EDcard study
Emil Durukan1,2,3, Christian Fuglesang S Jensen1, Maria Dons2,4
1Department of Urology, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark.
BJU International
|June 20, 2025
Summary
Men with erectile dysfunction (ED) have a high prevalence of myocardial impairment, specifically left ventricular (LV) systolic dysfunction. Over half of ED patients showed cardiac dysfunction, warranting further cardiovascular evaluation.
Area of Science:
- Cardiology
- Men's Health
- Echocardiography
Background:
- Erectile dysfunction (ED) is a common condition in men.
- Cardiovascular disease is a leading cause of morbidity and mortality.
- The relationship between ED and myocardial impairment requires further investigation.
Purpose of the Study:
- To determine the prevalence of myocardial impairment in men with ED.
- To compare cardiac function in men with ED to the general population.
- To utilize conventional and 2D speckle-tracking echocardiography for assessment.
Main Methods:
- Cross-sectional study design.
- Inclusion of 398 men with ED and 398 matched controls.
- Echocardiographic evaluation including LVEF and GLS.
Main Results:
- 58.3% of men with ED exhibited LV systolic dysfunction versus 25.6% in controls (P < 0.001).
- Higher prevalence of cardiac dysfunction in the ED group.
- 4.8% of men with ED were referred for further cardiovascular evaluation.
Conclusions:
- A significant proportion of men with ED present with myocardial impairment, particularly LV systolic dysfunction.
- These findings highlight a potential link between ED and cardiac health.
- Further research is needed to understand the long-term prognostic significance.
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