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Updated: Sep 18, 2025

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Ferulic Acid Use for Skin Applications: A Systematic Review.

Jennifer Roux1, Luke Horton2, Arash Babadjouni2,3

  • 1Ms. Roux is with the University of California Irvine School of Medicine in Irvine, California.

The Journal of Clinical and Aesthetic Dermatology
|June 20, 2025
PubMed
Summary

Ferulic acid (FA) shows promise in topical skincare for improving skin health, reducing redness, and hyperpigmentation. Further research is needed to fully understand its benefits and optimal application.

Keywords:
Ferulic acidanti-agingerythemapigmentationskintopical

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Area of Science:

  • Dermatology
  • Cosmetic Science

Background:

  • Ferulic acid (FA) is increasingly utilized in skincare for its antioxidant and anti-inflammatory properties.
  • Its clinical efficacy and optimal application in human subjects necessitate thorough evaluation.

Purpose of the Study:

  • To conduct a comprehensive review of existing literature on the topical application of ferulic acid in skincare.
  • To evaluate the effectiveness of ferulic acid in various dermatological conditions and cosmetic applications.

Main Methods:

  • A systematic literature search was performed using PubMed and Cochrane databases.
  • Inclusion criteria focused on human studies investigating ferulic acid's skin effects, published between January 1983 and June 2023.

Main Results:

  • Eighteen human studies indicated ferulic acid's efficacy in improving skin erythema, pigmentation, hydration, elasticity, and texture.
  • Ferulic acid demonstrated effectiveness both as a standalone ingredient and in combination therapies, across diverse subject populations.

Conclusions:

  • Current evidence supports ferulic acid formulations in mitigating skin erythema, hyperpigmentation, and aging signs in adults.
  • Limitations include small sample sizes, limited population diversity, and varied formulation compositions, highlighting the need for more rigorous studies.
  • Further research is essential to elucidate ferulic acid's mechanisms of action and optimize its use in treating skin conditions.