Related Experiment Video

Updated: Sep 18, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
06:46

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

Published on: June 21, 2017

7.5K

Copper-Catalyzed Highly Efficient and Asymmetric Allylic C-H Oxidation of 3-Aryl-Substituted Terminal Alkenes

Yibo Zhou, Pinhong Chen, Guosheng Liu

    Journal of the American Chemical Society
    |June 20, 2025
    PubMed

    More Related Videos

    Chemoselective Preparation of 1-Iodoalkynes, 1,2-Diiodoalkenes, and 1,1,2-Triiodoalkenes Based on the Oxidative Iodination of Terminal Alkynes09:54

    Chemoselective Preparation of 1-Iodoalkynes, 1,2-Diiodoalkenes, and 1,1,2-Triiodoalkenes Based on the Oxidative Iodination of Terminal Alkynes

    Published on: September 12, 2018

    7.8K
    A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis07:06

    A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis

    Published on: February 16, 2020

    8.3K

    Related Concept Videos

    Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide02:44

    Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide

    Alkenes are converted to 1,2-diols or glycols through a process called dihydroxylation. It involves the addition of two hydroxyl groups across the double bond with two different stereochemical approaches, namely anti and syn. Dihydroxylation using osmium tetroxide progresses with syn stereochemistry.
    10.9K
    Alkynes to Aldehydes and Ketones: Hydroboration-Oxidation02:47

    Alkynes to Aldehydes and Ketones: Hydroboration-Oxidation

    Introduction
    One of the convenient methods for the preparation of aldehydes and ketones is via hydration of alkynes. Hydroboration-oxidation of alkynes is an indirect hydration reaction in which an alkyne is treated with borane followed by oxidation with alkaline peroxide to form an enol that rapidly converts into an aldehyde or a ketone. Terminal alkynes form aldehydes, whereas internal alkynes give ketones as the final product.
    19.0K
    Reduction of Alkenes: Asymmetric Catalytic Hydrogenation02:17

    Reduction of Alkenes: Asymmetric Catalytic Hydrogenation

    Catalytic hydrogenation of alkenes is a transition-metal catalyzed reduction of the double bond using molecular hydrogen to give alkanes. The mode of hydrogen addition follows syn stereochemistry.
    The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...
    3.4K
    Reduction of Alkynes to cis-Alkenes: Catalytic Hydrogenation02:24

    Reduction of Alkynes to cis-Alkenes: Catalytic Hydrogenation

    Introduction
    Like alkenes, alkynes can be reduced to alkanes in the presence of transition metal catalysts such as Pt, Pd, or Ni. The reaction involves two sequential syn additions of hydrogen via a cis-alkene intermediate.
    8.2K
    Radical Substitution: Allylic Bromination01:27

    Radical Substitution: Allylic Bromination

    In organic synthesis, the formation of products can be altered by changing the reaction conditions. For example, a dibromo addition product is formed when propene is treated with bromine at room temperature. In contrast, propene undergoes allylic substitution in non-polar solvents at high temperatures to give 3-bromopropene. In order to avoid the addition reaction, the bromine concentration must be kept as low as possible throughout the reaction. This can be achieved using N-bromosuccinimide...
    5.5K
    α-Alkylation of Ketones via Enolate Ions01:10

    α-Alkylation of Ketones via Enolate Ions

    Ketones with α protons are deprotonated by strong bases like lithium diisopropylamide (LDA) to form enolate ions. The anion is stabilized by resonance, and its hybrid structure exhibits negative charges on the carbonyl oxygen and the α carbon. This ambident nucleophile can attack an electrophile via two possible sites: the carbonyl oxygen, known as O-attack, or the α carbon, known as C-attack. The nucleophilic attack via the carbanionic site is preferred. This is due to the...
    3.3K